Patients receiving zolpidem, was observed walking in a dream and more associated complex behavior: driving while half asleep, cooking and eating, phone calls, sexual intercourse with incomplete awakening with amnesia of these actions. The use of alcohol and other drugs with inhibitory effects on the together with zolpidem and zolpidem reception at doses exceeding the recommended dose evidently increases the risk of such behavior. If the patient reports the episode (s) of such behavior reception enanthate testosterone should be discontinued.
Coping After a course of reception within a few weeks of sedative / hypnotic drugs such as zolpidem, there may be some reduction in their sedative and hypnotic effects. Formation depending on the drug Benzodiazepine use and family drugs for their effects, especially prolonged, may result in the formation of physical and / or psychological dependence.Depending risk increases with the dose and duration of treatment, it is also higher in patients with a history of instructions of alcohol or other drugs, and non-drug substances. Such patients when receiving hypnotics should be under particularly close surveillance. However, the dependence can occur when using therapeutic doses and / or in patients without individual risk factors. In applying in therapeutic doses, the condition depending on the drug is very rare. In case of depending on at the termination of its reception may develop withdrawal symptoms, frequent symptoms are: insomnia, headache, and myalgia, dysphoria, anxiety, muscle tension and irritability. Less commonly (in more severe cases, withdrawal symptoms) are observed agitation or even episodes of confusion, derealization, depersonalization, numbness and paresthesias of extremities, extreme sensitivity to light, noise, physical contact, hallucinations and convulsions. Withdrawal may occur within a few days after cessation of drug treatment enanthate testosterone .
When receiving zolpidem (and other benzodiazepines short action) possible occurrence of withdrawal symptoms in the interval between the two methods, especially in high doses. Regardless of the indications for use of a combination of zolpidem with benzodiazepines increases the risk of addiction. There are reports of drug abuse cases. “Reflected “insomnia Transient syndrome cases until hypnotic treatment of insomnia in the form return in a stronger form. It can be combined with other reactions including mood changes, anxiety and dysphoria. It is important that the patient has been advised of the possibility of “rebound” phenomenon, which will reduce the concern about the occurrence of these symptoms when you stop taking the drug. The risk of accumulation ofbenzodiazepines and related compounds remain in the body for approximately five half-life periods. In elderly patients or patients with liver failure, a considerable increase in T 1/2 , which can lead to the accumulation of the drug in its repeated reception. Based on the features of the pharmacokinetics of zolpidem, in renal failure drug accumulation is not expected. Use in elderly patients In the appointment of benzodiazepines and related compounds elderly patients need to exercise caution due to the risk of sedation and / or miorelaksiruyuschego effects that can lead to falls from serious consequences. Patients should always be warned about the recommended duration of treatment is determined by the kind of insomnia.
Special precautions for the destruction of unused medicinal product
No need for special precautions during the destruction of unused medication .
Effects on ability to drive vehicles, machinery
During drug treatment must be careful when driving and occupation of other potentially hazardous activities that require high concentration and psychomotor speed reactions. To minimize the risk of negative influence of the drug on the ability to drive vehicles and enanthate testosterone perform other activities that require attention, should ensure uninterrupted sleep for at least 8 hours after dosing.
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